Formulation/Analytical Development
The Pharmacology Core provides a wide range of customized services for formulation and analysis of drugs and drug targets. These include services such as solubility/formulation, specialization in lipid based and parenteral formulations, formulation scale-up to Phase I requirements, UV/Vis spectrophotometry, HPLC and LC/MS, full assay development and Good Manufacturing Practices (GMP) validation and stability programs.
Validation
The Pharmacology Core provides a wide range of assays and validation services, including custom development.
Validated Methods
Lipids:
- Cholesterol
- Dipalmitoylphosphatidylcholine
- Distearoylphosphatidylcholine
- Distearoylphosphatidylcholine
- Distearoylphosphatidylethanolaminepoly(ethylene glycol)2000 (DSPE-PEG2000)
- Distearoylphosphatidylglycerol
- Distearoylphosphatidylglycerol
- Monostearoylphosphatidylcholine
- Sphingomyelin
Cytotoxics:
- Cytarabine
- Daunorubicin
- Doxorubicin
- Floxuridine
- Irinotecan
- Vincristine
- Vinorelbine
- 5-FU
Other:
Custom Validation Available
Please contact the Pharmacology Core
(pharma@bcprc.ca) for more information.
Pharmacology Service Request Form
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